Coagulation Resonance Analysis

The CORA™ system introduces a new technology—Coagulation Resonance Analysis—suited for on-demand monitoring in virtually any setting, from the hospital to ambulatory care clinics, physician offices, ambulances and combat zones. This approach is designed to produce timely, consistent results regardless of the operator or where the device is located, supporting enhanced patient care and clinical outcomes.

Measure all phases of hemostasis in whole blood.

The CORA hemostasis system continuously measures all phases of hemostasis as a net product of whole blood components—from the time the test begins until fibrin formation, through clot strengthening, and ultimately to maximum clot strength and lysis or clot breakdown. Coramed’s patented technique determines the viscoelastic properties of a clot by measuring the resonant frequency of a blood sample in response to vibration. The system then graphically and numerically shows the balance or degree of imbalance in the patient’s hemostasis, highlighting any areas of deficiency or excess. This information, which points to risk of hemorrhage or thrombosis, can then be used for therapeutic purposes.

CORA Parameters

CORA Parameters

Although new platelet tests are emerging, most standard laboratory tests are still plasma based and ignore the contribution of platelets. Many routinely ordered tests focus only on isolated components. By contrast, the CORA system will present a more comprehensive view of hemostasis, with the potential to more accurately identify and reasonably predict ischemic and bleeding events.

Compact and easy to use.

In the CORA system, patented, disposable cartridges with reagents in place fully automate the formerly labor-intensive process of preparing a patient blood sample for a test. The system is designed to minimize the need for training—there is no manual sample preparation needed. Instead, using a disposable dropper or transfer pipette, virtually any operator can add blood to a cartridge to perform a test.

What’s more, smart technology guides on-device patient data entry, performs all calculations and guards against operator mistakes such as the use of expired cartridges.

Perform multiple tests at once.

The CORA system includes discrete microfluidics cartridges capable of performing all current thrombelastography assays. Through innovative cartridge design, the CORA system can simultaneously perform four separate tests on a single disposable. In the past, this ability to run several assays at once would require multiple instruments and time-consuming sample preparation.

Appropriate for any environment—even mobile.

A small sample size and robust design make the next-generation CORA system well-suited for a wide range of settings. The instrument is immune to external vibration and requires no leveling or recalibration after it has been moved, enabling use throughout hospitals.

The CORA system has been designed for:

  • Hospitals
  • Physicians’ offices
  • Coumadin® clinics
  • Ambulatory surgery centers
  • Rural clinics
  • Combat zones
  • Diagnostic labs and ischemia-screening facilities
  • Dialysis centers
  • Veterinary clinics

Coumadin is a registered trademark of Bristol-Myers Squibb.

CORA Technology

The CORA system is designed to produce timely, reliable results from any operator in any location.